Scale-Up & Piloting

The commercial application of technology developed in the laboratory to industrial application requires the scaling up from the bench scale (.1 to 1L) to the industrial scale (10,000 – 1,000,000+ L), representing an increase of 10,000  to 1,000,000+ X, presenting a number of scale-up, process, equipment design, and technology risks.  The incremental scale up of process technologies to the pilot scale demonstrates the scalability of the technology and reduces the risks & costs associated with commercialization.

Advantages of Technology Piloting:

  • Validation of Lab Scale Results,
  • Demonstration of Process Scalability,
  • Scaling Solutions (sterility, heat transfer),
  • Effects of Technology Process Integration,
  • Commercialization Risk Reduction,

Bio-Process conducts pilot scale technology demonstrations, providing third party technology verification, process / technology scale-up assistance, pilot scale design / construction / operation services, as well as identification & solutions for process scale-up issues.

Technology  & Process Piloting Resources:

  • Experimental Design for Technology Scale-Up,
  • Pilot System Process & Equipment Design,
  • Equipment: Bio-Reactors, Tanks, Controls, Columns
  • Construction of Pilot Scale Processing System,
  • Pilot System Operation & Experimentation,
  • Analysis of Pilot Scale Results & Reporting,

Recent BPI Pilot Scale Projects:

  • Commercial Demonstration of Biomass to Ethanol Process,
  • Production of Lactose Fermentation Organisms from Whey,
  • Production & Concentration of Acetate from Xylose Sugars,
  • Processing & Conversion of MSW Derived Fiber to Ethanol,
  • Low Temperature Steep Delignification (LTSD) of Switch Grass,
  • Separation & Conversion of Potato Processing Waste Water,

Bio-Process can provide the equipment, staff, design, and operations to scale-up, demonstrate, and pilot process technologies and systems.  Please contact us to learn more about our technology scale-up services and pilot systems.