Scale-Up & Piloting
The commercial application of technology developed in the laboratory to industrial application requires the scaling up from the bench scale (.1 to 1L) to the industrial scale (10,000 – 1,000,000+ L), representing an increase of 10,000 to 1,000,000+ X, presenting a number of scale-up, process, equipment design, and technology risks. The incremental scale up of process technologies to the pilot scale demonstrates the scalability of the technology and reduces the risks & costs associated with commercialization.
Advantages of Technology Piloting:
- Validation of Lab Scale Results,
- Demonstration of Process Scalability,
- Scaling Solutions (sterility, heat transfer),
- Effects of Technology Process Integration,
- Commercialization Risk Reduction,
Bio-Process conducts pilot scale technology demonstrations, providing third party technology verification, process / technology scale-up assistance, pilot scale design / construction / operation services, as well as identification & solutions for process scale-up issues.
Technology & Process Piloting Resources:
- Experimental Design for Technology Scale-Up,
- Pilot System Process & Equipment Design,
- Equipment: Bio-Reactors, Tanks, Controls, Columns
- Construction of Pilot Scale Processing System,
- Pilot System Operation & Experimentation,
- Analysis of Pilot Scale Results & Reporting,
Recent BPI Pilot Scale Projects:
- Commercial Demonstration of Biomass to Ethanol Process,
- Production of Lactose Fermentation Organisms from Whey,
- Production & Concentration of Acetate from Xylose Sugars,
- Processing & Conversion of MSW Derived Fiber to Ethanol,
- Low Temperature Steep Delignification (LTSD) of Switch Grass,
- Separation & Conversion of Potato Processing Waste Water,
Bio-Process can provide the equipment, staff, design, and operations to scale-up, demonstrate, and pilot process technologies and systems. Please contact us to learn more about our technology scale-up services and pilot systems.

