Pilot Facility
Bio-Process Group’s pilot facility serves as a crucial bridge in the research and development process between lab-scale discoveries and real-world applications. Our applied science and engineering staff works with clients at the pilot-scale for testing methods prior to full-scale operation, allowing us to evaluate feasibility, time, cost, adverse events, and statistical variability of yields in order to optimize your design.
Advantages of Technology Piloting
Validation of Lab Results
By transitioning bio-engineering solutions from the confined laboratory environment to our pilot facility, we can assess their feasibility, effectiveness, and scalability in a more representative setting.
Reduction of Commercialization Risk
By addressing any potential issues or limitations early on, we help you make informed decisions and refine your approach, ensuring a smoother transition from concept to market-ready solutions.
Optimization and Process Improvement
Operating at pilot-scale, we can fine-tune various parameters such as temperature, pressure, pH, and agitation, among others, to maximize efficiency and yield. This iterative process allows us to identify bottlenecks, troubleshoot issues, and implement improvements that can significantly enhance overall process performance.
Bio-Process Scale-Up Challenges
Fermentation Scale-Up
Scaling up fermentation processes from the laboratory to larger volumes presents unique challenges that must be carefully addressed. Our team specializes in providing comprehensive scaling solutions for your process technology, addressing critical aspects such as maintaining sterility, optimizing heat transfer, and ensuring effective oxygen transfer.
Process Integration
Process integration involves seamlessly combining various unit operations, equipment, and steps within a larger bio-processing framework. This integration is essential to achieve a cohesive and efficient overall process. We ensure smooth transitions between different stages of the bio-process, minimizing hold-ups, reducing process variability, and maximizing productivity.
Pilot Facility Capabilities and Equipment
Separations
Basket Centrifuges
MVR Evaporator
Filter presses: 0.1 cubic feet and 4 cubic feet capacity
Pulping
30 L stainless steel LTSD pulper
1200 L stainless steel LTSD pulper
2000 L stainless steel LTSD pulper
100 HP Deflaker to fiberize wood/bamboo/tobacco stalk chips piped to 3000 L stainless steel tank
Heating and Mixing
2 100 gallon jacketed stainless steel tanks
80 gallon stirred reactor
Fermentation
3 1.5 L Multigen bio-reactors'
2 8 L glass bio-reactors
3 16 L stainless steep SIP bio-reactors
Contact us if you would like more information about our resources or if you would like to schedule a tour of our facilities.