Pilot Facility

Bio-Process Group’s pilot facility serves as a crucial bridge in the research and development process between lab-scale discoveries and real-world applications. Our applied science and engineering staff works with clients at the pilot-scale for testing methods prior to full-scale operation, allowing us to evaluate feasibility, time, cost, adverse events, and statistical variability of yields in order to optimize your design.

Advantages of Technology Piloting

Validation of Lab Results

By transitioning bio-engineering solutions from the confined laboratory environment to our pilot facility, we can assess their feasibility, effectiveness, and scalability in a more representative setting.

Reduction of Commercialization Risk

By addressing any potential issues or limitations early on, we help you make informed decisions and refine your approach, ensuring a smoother transition from concept to market-ready solutions.

Optimization and Process Improvement

Operating at pilot-scale, we can fine-tune various parameters such as temperature, pressure, pH, and agitation, among others, to maximize efficiency and yield. This iterative process allows us to identify bottlenecks, troubleshoot issues, and implement improvements that can significantly enhance overall process performance.

Bio-Process Scale-Up Challenges

Fermentation Scale-Up

Scaling up fermentation processes from the laboratory to larger volumes presents unique challenges that must be carefully addressed. Our team specializes in providing comprehensive scaling solutions for your process technology, addressing critical aspects such as maintaining sterility, optimizing heat transfer, and ensuring effective oxygen transfer.

Process Integration

Process integration involves seamlessly combining various unit operations, equipment, and steps within a larger bio-processing framework. This integration is essential to achieve a cohesive and efficient overall process. We ensure smooth transitions between different stages of the bio-process, minimizing hold-ups, reducing process variability, and maximizing productivity.

Pilot Facility Capabilities and Equipment

Bio-Process Group's ultrafiltration skid

Featured: Membrane Separations

Bio-Process Group offers an ultrafiltration and reverse osmosis skid available for lease and for pilot studies at our pilot facility.

Separations

  • Basket Centrifuges

  • MVR Evaporator

  • Filter presses: 0.1 cubic feet and 4 cubic feet capacity

Pulping

  • 30 L stainless steel LTSD pulper

  • 1200 L stainless steel LTSD pulper

  • 2000 L stainless steel LTSD pulper

  • 100 HP Deflaker to fiberize wood/bamboo/tobacco stalk chips piped to 3000 L stainless steel tank

  • Learn more about our pulping projects

Jacketed stainless steel tanks at the Bio-Process Group pilot plant

Heating and Mixing

  • 2 100 gallon jacketed stainless steel tanks

  • 80 gallon stirred reactor

Fermentation

  • 3 1.5 L Multigen bio-reactors'

  • 2 8 L glass bio-reactors

  • 3 16 L stainless steep SIP bio-reactors

Contact us if you would like more information about our resources or if you would like to schedule a tour of our facilities.